Targeted & controlled bone healing

Kuros’ Surface Science Technology

Our calcium phosphates are based on unique and proprietary synthetic surface science technology. These technologies have a submicron surface topograpy that directs bone formation.

The surface topography has been demonstrated to stimulate the body to form bone in a safe, localized and accelerated manner. A substantial number of clinically relevant and predictive preclinical studies in small and large animals have demonstrated that the surface science platform  leads to progressive bone formation and implant resorption and is equivalent to the current gold standard autograft. 

Publications on Surface Science Technology

Barbieri D, Yuan H, Ismailoglu A, de Bruijn JD.
Comparison of two moldable calcium phosphate-based bone graft materials in a non-instrumented canine interspinous implantation model.
Tissue Eng Part A, PMID 28132596, DOI 10.1089/ten.TEA.2016.0347 (2017). Duan R, Barbieri D, Luo X, Weng J, de Bruijn JD, Yuan H.
Submicron-surface structured tricalcium phosphate ceramic enhances bone regeneration in canine spine environment.
J Orthop Res. 34(11):1865-1873 (2016) doi:10.1002/jor.23201, PMID: 26896645. Zhang, J., Barbieri, D., Ten Hoopen, H., De Bruijn, J. D., Van Blitterswijk, C. A., & Yuan, H.
Microporous calcium phosphate ceramics driving osteogenesis through surface architecture.
Journal of Biomedical Materials Research - Part A (2015), 103(3), 1188-1199. Shiwaku Y, Neff L, Nagano K, Takeyama K, de Bruijn J, Dard M, Gori F, Baron R.
The crosstalk between osteoclasts and osteoblasts is dependent upon the composition and structure of biphasic calcium phosphates, PLoS One 10(7):e0132903 (2015) PMID: 26193362.
PLoS One 10(7):e0132903 (2015) PMID: 26193362.
Kuros Biosciences AG
Wagistrasse 25, 8952 Schlieren, Switzerland
Tel: +41 44 733 47 47   Fax: +41 44 733 47 40   Email: info@kurosbio.com

About Kuros

  1. Overview
  2. Executive Committee
  3. Board
  4. Careers

Products

  1. MagnetOs

Pipeline

  1. Pipeline
  2. Spinal fusion
    KUR-113
  3. Fracture repair
    KUR-111
    KUR-113
  4. Surgical Sealants
    Neuroseal (KUR-023)

Technologies

  1. Surface Science Technology
  2. Fibrin-Based
  3. Synthetic Cross-Linking Technology
  4. Immune Modulation

Partnerships

  1. Collaborations
  2. Business Development

Investors

  1. Share price
  2. Regulatory filings
  3. Reports & Presentations
  4. Analysts
  5. Calendar
  6. Corporate governance
  7. Stay informed

News

  1. Press releases
  2. Conferences & Events

Contact

  1. Location
Surface Science Technology

Kuros’ Surface Science Technology

Our calcium phosphates are based on unique and proprietary synthetic surface science technology. These technologies have a submicron surface topograpy that directs bone formation.

The surface topography has been demonstrated to stimulate the body to form bone in a safe, localized and accelerated manner. A substantial number of clinically relevant and predictive preclinical studies in small and large animals have demonstrated that the surface science platform  leads to progressive bone formation and implant resorption and is equivalent to the current gold standard autograft. 

Publications on Surface Science Technology

Barbieri D, Yuan H, Ismailoglu A, de Bruijn JD.
Comparison of two moldable calcium phosphate-based bone graft materials in a non-instrumented canine interspinous implantation model.
Tissue Eng Part A, PMID 28132596, DOI 10.1089/ten.TEA.2016.0347 (2017). Duan R, Barbieri D, Luo X, Weng J, de Bruijn JD, Yuan H.
Submicron-surface structured tricalcium phosphate ceramic enhances bone regeneration in canine spine environment.
J Orthop Res. 34(11):1865-1873 (2016) doi:10.1002/jor.23201, PMID: 26896645. Zhang, J., Barbieri, D., Ten Hoopen, H., De Bruijn, J. D., Van Blitterswijk, C. A., & Yuan, H.
Microporous calcium phosphate ceramics driving osteogenesis through surface architecture.
Journal of Biomedical Materials Research - Part A (2015), 103(3), 1188-1199. Shiwaku Y, Neff L, Nagano K, Takeyama K, de Bruijn J, Dard M, Gori F, Baron R.
The crosstalk between osteoclasts and osteoblasts is dependent upon the composition and structure of biphasic calcium phosphates, PLoS One 10(7):e0132903 (2015) PMID: 26193362.
PLoS One 10(7):e0132903 (2015) PMID: 26193362.